JBC Enzymology

Enzymology In Press

EBNA1-dependent recruitment of Orc on OriP of Epstein-Barr virus with purified proteins: Stimulation by Cdc6 through Its direct niteraction with EBNA1

Kenji Moriyama, Naoko Yoshizawa-Sugata, Chikashi Obuse, Toshiki Tsurimoto, Hisao Masai

First published on May. 14, 2012

Tight Interplay Among SAMHD1 Level, Cellular dNTP Levels and HIV-1 Proviral DNA Synthesis Kinetics in Human Primary Monocyte-Derived Macrophages

Baek Kim, Laura A. Nguyen, Waaqo Daddacha, Joseph A. Hollenbaugh

First published on May. 14, 2012

Binding of the phytopolyphenol piceatannol disrupts β/γ subunit interactions and the rate limiting step of steady state rotational catalysis in the Escherichia coli F1-ATPase

Mizuki Sekiya, Robert K. Nakamoto, Mayumi Nakanishi-Matsui, Masamitsu Futai

First published on May. 11, 2012

Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid: cholesterol acyltransferase

Christina Lang, Elena Rastew, Bjöern Hermes, Enrico Siegbrecht, Robert Ahrends, Sangeeta Banerji, Antje Flieger

First published on May. 11, 2012

Regulatory domain determinants that control PKD1 activity

Vitalyi O. Rybin, Jianfen Guo, Erin Harleton, Fan Zhang, Susan F. Steinberg

First published on May. 11, 2012

The Human POLB Gene is Mutated in a High Percentage of Colorectal Tumors

Katherine A. Donigan, Ka-Wai Sun, Antonia A. Nemec, Drew L. Murphy, Xiangyu Cong, Veronika Northrup, Daniel Zelterman, Joann B. Sweasy

First published on May. 10, 2012

Linear chromosome generating system of Agrobacterium tumefaciens C58: Protelomerase generates and protects hairpin ends

Wai Mun Huang, Jeanne DaGloria, Heather Fox, Qiurong Ruan, John Tillou, Ke Shi, Hideki Aihara, John Aron, Sherwood Casjens

First published on May. 10, 2012

Dimerization of matrix metalloproteinase-2(MMP-2): functional implication in MMP-2 activation

Bon-Hun Koo, Yeon Hyang Kim, Jung Ho Han, Doo-Sik Kim

First published on May. 10, 2012

Paper of the year

Best of JBC

Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase

Rebecca D. Powell, Paul J. Holland, Thomas Hollis, Fred W. Perrino

First published on Nov. 7, 2011

Author Profiles

Qi Zhang

Complex biotransformations catalyzed by radical S-adenosylmethionine enzymes

Marco Bellinzoni

3-Keto-5-aminohexanoate Cleavage Enzyme

Clinton D. Orebaugh

The TREX1 Exonuclease R114H Mutation in Aicardi-Goutières Syndrome and Lupus Reveals Dimeric Structure Requirements for DNA Degradation Activity

Nisha A. Cavanaugh

Molecular Insights into DNA Polymerase Deterrents for Ribonucleotide Insertion

Classics

Reversible Phosphorylation and Kinase Cascades: the Work of Edwin G. Krebs

Nicole Kresge, Robert D. Simoni, Robert L. Hill

First published on Oct. 28, 2005

The Regulation of Adenyl Cyclase by G-protein: the Work of Alfred G. Gilman

Nicole Kresge, Robert D. Simoni, Robert L. Hill

First published on Nov. 4, 2005

The Waterfall Sequence for Blood Clotting: the Work of Earl W. Davie

Nicole Kresge, Robert D. Simoni, Robert L. Hill

First published on Dec. 1, 2006

Blood Clotting and Coagulation Factors: The Work of Yale Nemerson

Nicole Kresge, Robert D. Simoni, Robert L. Hill

First published on Jul. 1, 2011

Reflections

Wandering through the Laboratory

Philip W. Majerus

First published on Dec. 17, 2010

Five Decades with Glutathione and the GSTome

Bengt Mannervik

First published on Jan. 13, 2012

The Story of Glutamine Synthetase Regulation

Earl R. Stadtman

First published on Oct. 3, 2001

A Brief Historical Review of the Waterfall/Cascade of Blood Coagulation

Earl W. Davie

First published on Oct. 21, 2003

Papers of the Week

How to Fit In: DNA Polymerase Strategies to Ensure Proper Nucleotide Insertion♦

First published on Sep. 2, 2011

BP: Bacterial Petroleum?♦

First published on May. 27, 2011

The Accidental Tourist: A Tale of Antibody Diversity♦

First published on Jul. 8, 2011

Catalytic Tales from Cryptic Sequences: Domain of Unknown Function (DUF)♦

First published on Jul. 29, 2011

Enzymology at the JBC

F. Guengerich

Enzymology is a classic focus of the JBC. Many of the seminal papers in the field of enzymology have been published in the JBC, going back to the first half of the 20^th century.

We are still very interested in research on enzymology and intend to remain the premier journal in this area.

Minireviews

Structure-Function Relationships in [FeFe]-Hydrogenase Active Site Maturation

Yvain Nicolet, Juan C. Fontecilla-Camps

First published on Mar. 2, 2012

Metal Transport across Biomembranes: Emerging Models for a Distinct Chemistry

José M. Argüello, Daniel Raimunda, Manuel González-Guerrero

First published on Mar. 2, 2012

Most Cited

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V. S. Sankaranand, Shrikant Anant, Manabu Sugai, Kazuo Kinoshita, Nicholas O. Davidson, Tasuku Honjo

First published on Jun. 25, 1999

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

Margaret F. Favata, Kurumi Y. Horiuchi, Elizabeth J. Manos, Andrea J. Daulerio, Deborah A. Stradley, Wendi S. Feeser, Drew E. Van Dyk, William J. Pitts, Richard A. Earl, Frank Hobbs, Robert A. Copeland, Ronald L. Magolda, Peggy A. Scherle, James M. Trzaskos

First published on Jul. 17, 1998

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enzymology

Enzymology In Press

Paper of the year

Author Profiles

Classics

Reflections

Papers of the Week

Enzymology at the JBC

Minireviews

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