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Tasida Barfoot, Timothy J. Herdendorf, Bryanna R. Behning, Bradley A. Stohr, Yang Gao, Kenneth N. Kreuzer, Scott W. Nelson
First Published on Aug 04, 2015
Veronica Saez-Jimenez, Maria Camilla Baratto, Rebecca Pogni, Jorge Rencoret, Ana Gutierrez, Jose Ignacio Santos, Angel T. MartInez, Francisco Javier Ruiz-Duenas
First Published on Aug 03, 2015
Andrea C. Rodriguez, Seok-Ho Yu, Bin Li, Hicham Zegzouti, Jennifer J. Kohler
First Published on Aug 03, 2015
Shanteri Singh, Karolina Michalska, Lance Bigelow, Michael Endres, Madan K. Kharel, Gyorgy Babnigg, Ragothaman M. Yennamalli, Craig A. Bingman, Andrzej Joachimiak, Jon S. Thorson, George N. Phillips Jr.
First Published on Aug 03, 2015
Lin Lin, Srila Gopal, Anish Sharda, Freda Passam, Sheryl R. Bowley, Jack Stopa, Guangpu Xue, Cai Yuan, Barbara C. Furie, Robert Flaumenhaft, Mingdong Huang, Bruce Furie
First Published on Aug 03, 2015
David A. Meekins, Madushi Raththagala, Kyle D. Auger, Benjamin D. Turner, Diana Santelia, Oliver Kötting, Matthew S. Gentry, Craig W. Vander Kooi
First Published on Jul 31, 2015

Best of 2014

Ingrid M. Verhamme, Paul E. Bock
October 03, 2014 The Journal of Biological Chemistry, 289, 28006-28018.

PAPERS OF THE WEEK

REPORTS

Mohammad T. Mazhab-Jafari, Christopher B. Marshall, Jason Ho, Noboru Ishiyama, Vuk Stambolic, Mitsuhiko Ikura
First Published on Mar 19, 2014
Patrick M. Shih, Jan Zarzycki, Krishna K. Niyogi, Cheryl A. Kerfeld
First Published on Feb 20, 2014

CLASSICS

Yale Nemerson
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 24, 2011
E. Peter Geiduschek
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 24, 2010
William P. Jencks
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 29, 2010
Yasutomi Nishizuka
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 22, 2010
Christopher T. Walsh
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 08, 2010
Jean D. Wilson
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Sep 24, 2010
Bert L. Vallee
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 20, 2010
Vernon L. Schramm
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 18, 2010
Isao Yamazaki
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 14, 2010
Harry Beevers. Photograph courtesy of Purdue University Libraries, Karnes 
Archives and Special Collections.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 07, 2010
Paul R. Schimmel
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 02, 2010
William J. Rutter. Photo courtesy of the University of Utah Alumni 
Association.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 25, 2009
Judith P. Klinman
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 02, 2009
Frederic M. Richards
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Sep 18, 2009
Perry Frey
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 14, 2009
Brian Matthews
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 19, 2009
Mahlon Hoagland
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 12, 2009
Feodor Lynen
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 29, 2009
Charles T. Esmon
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 01, 2009
Johan Stenflo
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 24, 2009
Nick Pace
Nicole Kresge, Robert D. Simoni, Robert L. Hil
First Published on Sep 12, 2008
William L. Smith
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 09, 2008
John W. Suttie
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 18, 2008
Philip W. Majerus
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Mar 14, 2008
Jeffrey I. Gordon
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 04, 2008
Daniel E. Koshland
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Sep 07, 2007
Paul Talalay. Photo courtesy of Oregon State University.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 10, 2007
George R. Stark
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 03, 2007
Celia and Herbert Tabor
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 03, 2007
Charles C. Richardson
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jul 06, 2007
Maxine Singer
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 15, 2007
Nathan O. Kaplan
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 01, 2007
James C. Wang
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 25, 2007
Howard K. Schachman
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 18, 2007
Mary Ellen Jones
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 04, 2007
Robert T. Schimke
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 20, 2007
Sidney Altman
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Feb 09, 2007
Bruce Alberts
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 19, 2007
I. Robert Lehman
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 05, 2007
Jack E. Dixon
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 15, 2006
M. Daniel Lane
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 01, 2006
Earl W. Davie
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 24, 2006
Minor J. Coon
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 17, 2006
W. Wallace Cleland
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 10, 2006
Michael J. Chamberlin. Photo courtesy of /Sigma Xi Today/.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 03, 2006
Avram Hershko. Photo courtesy of Technion-Israel Institute of Technology. 
Photographed by Miki Koren.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Sep 29, 2006
Robert Bruce Merrifield. Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 23, 2006
Paul D. Boyer. Photo courtesy of UCLA photography.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jun 02, 2006
Irwin Fridovich.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on May 26, 2006
Line art representation of a quill pen. Photo credit: Wikimedia Commons: 
http://commons.wikimedia.org/wiki/File:Quill_%28PSF%29.png.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 21, 2006
Peter Reichard. Photo reprinted with permission from the /Annual Review of 
Biochemistry/, Vol. 64. ©1995 by Annual Reviews (www.annualreviews.org).
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 14, 2006
Jerard Hurwitz. Photograph courtesy of the Memorial Sloan-Kettering Cancer 
Center.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Apr 07, 2006
Lester J. Reed. Photo courtesy of The University of Texas at Austin.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Feb 17, 2006
Robert L. Hill
Nicole Kresge, Robert D. Simoni
First Published on Feb 03, 2006
Salih J. Wakil
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 27, 2006
Efraim Racker. Photo credit: Obituary (1991), /Cell. Physiol. Biochem./ *1*, 
237.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 20, 2006
Phase microscopic appearance of intact erythrocytes on the /left/, 
“ghosts” in the /center/, and “enzyme” on the /right/. The optical 
cdonditions were the same in all three photographs. Taken from Post /et al./ 
(1960), /J. Biol. Chem./ *235*, 1796-1802.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Jan 06, 2006
Saul Roseman
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 30, 2005
Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 02, 2005
Reprinted with permission from the /Annual Review of Biochemistry/, Vol. 63. 
©1994 by Annual Reviews, www.annualreviews.org.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 18, 2005
Photo of Charles Yanofsky.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 11, 2005
Alfred Gilman at the 1994 Nobel Prize awards.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 28, 2005
Photo of Edwin G. Krebs, courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 21, 2005
Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Oct 07, 2005
Giulio L. Cantoni. Photo courtesy of The NIH Record.
Nicole Kresge, Herbert Tabor, Robert D. Simoni, Robert L. Hill
First Published on Sep 16, 2005
William Zev Hassid, professor of biochemistry at the University of California 
Berkeley. Credit: Bob Lackenbach, University of California Berkeley (1951 or 
earlier).
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 19, 2005
Photo courtesy of the University of California Berkeley.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 12, 2005
Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Aug 05, 2005
Esmond E. Snell.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Mar 25, 2005
Britton Chance. Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Dec 03, 2004
Emil L. Smith. Photo courtesy of the National Library of Medicine.
Nicole Kresge, Robert D. Simoni, Robert L. Hill
First Published on Nov 12, 2004
Birgit Vennesland. Photo credit: Birgit Vennesland//Annual Review of Plant 
Physiology/.
Robert D. Simoni, Robert L. Hill, Martha Vaughan
First Published on Jan 10, 2004
Philip P. Cohen. Photo courtesy of the National Library of Medicine.
Robert D. Simoni, Robert L. Hill, Martha Vaughan, Herbert Tabor
First Published on Dec 24, 2003
James Sumner. Reprinted with permission from Science Source.
Robert D. Simoni, Robert L. Hill, Martha Vaughan
First Published on Aug 23, 2002
Christian A. Herter. Photo courtesy of the National Library of
Medicine.
Robert D. Simoni, Robert L. Hill, Martha Vaughan
First Published on Apr 19, 2002
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REFLECTIONS

*Photo of the author, Perry Allen Frey.*
Perry Allen Frey
First Published on Mar 09, 2015
*Jackie Corbin playing football for Tennessee Tech in 1961.*
Jackie Corbin
First Published on Dec 11, 2014
*Maurice J. Bessman (1973) shown brewing a cup of joe bearing his initials, 
“MJB” (see coffee label at rear).*
Myron F. Goodman
First Published on Aug 26, 2014
*Oxygenase friends and pioneers.* /Left/, I. C. “Gunny” Gunsalus in 1976. 
/Center/, Lawrence Que, Jr., in 2013. /Right/, Eckard Münck in 1977.
John D. Lipscomb
First Published on Apr 15, 2014
*Miroslav Radman (/left/), the author (/center/), and Philip Hanawalt 
(/right/) at the Princess Takamatsu Symposium on DNA Repair and Human Cancers 
held in Tokyo in November 2009.*
Errol C. Friedberg
First Published on Apr 07, 2014
*The author reading a poem in 1960 at Jacques Monod's 50th birthday.* From 
/left/ to /right/: Sarah Rapkine, Jacques Monod, François Jacob, the author, 
and François Gros. The photo was provided by the Fonds d'Archives Madeleine 
Brunerie at the Institut Pasteur.
Jean-Pierre Changeux
First Published on Jul 22, 2013
*Edith Wilson uses a Cary recording spectrophotometer in the Department of 
Biochemistry at UC-Berkeley in 1958.*
Edith Wilson Miles
First Published on Feb 20, 2013
*Walter Oswaldo Cruz, my tutor during my initial period as a medical 
student.*
Leopoldo de Meis
First Published on Mar 16, 2012
*Participants in the conference on glutathione in Schloss Reisensburg in 
Germany in 1978.* The front row features, from left to right, Dagmar 
Siliprandi, Alton Meister, Sir Hans Krebs, Bengt Mannervik, Albrecht Wendel, 
and Leopold Flohé.
Bengt Mannervik
First Published on Jan 13, 2012
In 1972, Roy Vagelos (/left/) was elected to the National Academy of 
Sciences.
Philip W. Majerus
First Published on Dec 17, 2010
/Left panel/, Lipmann laboratory in 1968: Chris Walsh at age 24, Fritz 
Lipmann, and Dr. Wieland Gevers. /Right panel/, Robert H. Abeles and Chris 
Walsh in 1989.
Christopher T. Walsh
First Published on Jul 01, 2010
In 1200 B.C., a blue-purple dye was discovered and quickly became a favorite. 
This dye, Tyrian purple, also known as royal purple, was a major commercial 
item in Asia Minor and was very expensive. The dye was produced by shellfish 
of the murex family.
Lowell P. Hager
First Published on Mar 09, 2010
*γ-Glutamyl cycle proposed by Alton Meister (12).* The cycle is involved 
primarily in the turnover of glutathione, /i.e./ glutathione synthesis and 
degradation. /AA/, amino acid.
Naoyuki Taniguchi
First Published on Oct 19, 2009
*Redox-linked p/Ka/ associated with reduction of the active-site disulfide of 
dihydrolipoamide dehydrogenase.*
Rowena G. Matthews
First Published on Jul 13, 2009
*Ed Krebs (/left/) and Eddy Fischer (/right/) in 1992 upon hearing that they 
have been awarded the Nobel Prize for Physiology or Medicine.*
Philip Cohen
First Published on Jun 10, 2009
*Bettie Sue Siler Masters at the University of Sheffield in the United 
Kingdom as a graduate student admiring her favorite flavoprotein, 
NADPH-cytochrome P450 reductase, then known as TPNH-cytochrome /c/ 
reductase.* After spending 6 months preparing sufficient quantities of the 
enzyme, I worked in collaboration with Drs. Quentin H. Gibson and Vincent 
Massey to obtain stopped-flow kinetics and static spectrophotometric data, 
respectively.
Bettie Sue Siler Masters
First Published on Apr 27, 2009
Thioredoxin and glutaredoxin systems. Figure courtesy of the Beckwith Lab, 
Department of Microbiology and Immunology, Harvard Medical School.
Jon Beckwith
First Published on Jan 07, 2009
*The Stadtman laboratory (officially called the Laboratory of Biochemistry of 
the National Heart Institute) in 1966.* Terry and Earl Stadtman are second 
and third from the left, respectively, in the second row; I am second from 
the left in the back row.
Robert L. Switzer
First Published on Oct 23, 2008
The thiazolium ion loses a proton at C-2 to form a zwitterion that has a 
carbene resonance form. This resonance hybrid species is the catalytic form 
in biochemical reactions catalyzed by thiamine diphosphate.
Ronald Breslow
First Published on Sep 10, 2008
*Flow of genetic information from DNA to the tRNA-mRNA on the ribosome.*
Paul Schimmel
First Published on Jul 18, 2008
Schematic representation of the minimum reaction mechanism for the hydrolysis 
of a dinucleoside by ribonuclease A (as discussed in text). PypN, pyrimidine 
dinucleoside; Py2′:3′p, pyrimidine cyclic phosphate; Py3′p, pyrimidine 
3′-phosphate; E and E′, different enzyme conformations.
Gordon G. Hammes
First Published on May 13, 2008
Photo courtesy of the author.
Christopher K. Mathews
First Published on May 05, 2008
Robert A. Alberty (left) and Carl Frieden watch (or pretend to watch) the 
change in absorbance due to the conversion of malate to fumarate at 250 nm on 
a Beckman DU spectrophotometer. By inserting a bucking out circuit in the 
line, the transmittance from 90 to 100% was recorded on the full scale of the 
chart. This increased the sensitivity of measurement so that the chart 
recorder measured 0–0.1 absorbance unit almost linearly. Special 
logarithmic chart paper had to be used. The photograph was taken in 1953.
Carl Frieden
First Published on Apr 28, 2008
*Enzymic formation of /cis/,/cis/-muconic acid from catechol.*
Osamu Hayaishi
First Published on Apr 04, 2008
Photo courtesy of Fox Chase Cancer Center.
I. A. Rose
First Published on Mar 03, 2006
Prospect of grant request being funded in relation to the originality of the 
research proposal.
Howard K. Schachman
First Published on Feb 03, 2006
Crystal structure of the enzyme PNPase. Photo credit: Wikimedia Commons: 
http://commons.wikimedia.org/wiki/File:Crystal_structure_1E3P.jpg.
Uriel Z. Littauer
First Published on Nov 18, 2005
Charles Huggins (left) and the author in the Ben May Laboratories for Cancer 
Research at the University of Chicago in 1964. The Chinese inscription in the 
panel (left) may be translated: “To make discoveries is man's calling,” 
or as Huggins put it succinctly in his laboratory motto: “Discovery is our 
Business.”
Paul Talalay
First Published on Jun 07, 2005
Photo courtesy of the author.
Boris Magasanik
First Published on Apr 19, 2005
Photo credit: Wikimedia Commons: 
http://commons.wikimedia.org/wiki/File:EKatzir771.jpg.
Ephraim Katchalski-Katzir
First Published on Feb 17, 2005
Cyanate, formed from urea, carbamylates proteins.
George R. Stark
First Published on Jan 04, 2005
Photo credit: Office of History, National Institutes of Health.
Leon A. Heppel
First Published on Sep 14, 2004
Harland Wood, circa 1991. (Reprinted with permission of the Cleveland Plain 
Dealer newspaper.)
M. Daniel Lane
First Published on May 27, 2004
Photo courtesy of Massachusetts Institute of Technology Department of 
Chemistry.
Robert A. Alberty
First Published on Apr 08, 2004
Photo courtesy of Rockefeller University.
Christian de Duve
First Published on Mar 15, 2004
*Equilibrium perturbation of NADPH level when malate-2-/d/ and unlabeled 
NADPH are used with malic enzyme (**13**).*
W. Wallace Cleland
First Published on Oct 28, 2003
*Professor Hans Neurath (1909-2002).*
Earl W. Davie
First Published on Oct 21, 2003
*Christian B. Anfinsen, Ephraim Katzir-Katchalski, and Michael Sela (1986).*
Michael Sela
First Published on Sep 17, 2003
Harland Goff Wood.
Paul Berg
First Published on Jul 31, 2003
Scheme for the separation of components required for synthesis of DNA by DNA 
polymerase.
I. R. Lehman
First Published on Jun 05, 2003
Photo courtesy of the Michigan State University Department of Chemistry.
F. H. Westheimer
First Published on Jan 29, 2003
*Early speculation on how a suppressor mutation might restore synthesis of an 
active tryptophan synthetase protein (/TS/) in mutant /td2/ but not mutant 
/td1/.* It was assumed that the /td/gene was altered differently in the two 
mutants. This allowed the product of a specific suppressor gene to act on the 
altered template of mutant /td2/, the CRM+ mutant, to produce an active 
tryptophan synthetase enzyme. Copied with permission from Academic Press 
(12).
Charles Yanofsky
First Published on Jan 29, 2003
Bernard L. Horecker
First Published on Oct 25, 2002
Jacques Monod (left) and Georges Cohen (right) measuring β-galactosidase 
activity spectrophotometrically (circa 1954).
Georges N. Cohen
First Published on Oct 25, 2002
*The ATP synthase.* The enzyme from/E. coli/ has an F1 portion with subunits 
designated as α3β3γδε. When separated it acts as an ATPase. The F0 
portion subunits are designated as ab2c9–12. The passage of protons, at the 
interface of the a subunit and the ring of c subunits, causes a rotation of 
the c and attached ε and γ subunits relative to the rest of the enzyme. The 
asymmetric γ subunit (/yellow/ and /light green/) extends through the center 
of the α3β3cluster. The b2 and δ subunits serve as a stator. The rotation 
of the γ subunit results in sequential conformational changes of the 
catalytic sites that promote ADP and Pi binding, ATP formation, and ATP 
release. The mitochondrial and chloroplast enzymes are similar, except the F0 
portion has more subunits. The three catalytic sites are principally on the 
β subunits at an interface with the α subunits. The α subunits also have 
three non-catalytic sites that bind nucleotides. The figure is from Ref. 112 
(copyright 2001, National Academy of Sciences, U. S. A.).
Paul D. Boyer
First Published on Aug 13, 2002
*Inscription on bronze plaque given annually to recipients of the William C. 
Rose Award in Biochemistry.* The inscription directly below Dr. Rose's 
portrait is an excerpt from an article that appeared in 1935 in /The Journal 
of Biological Chemistry/ (/J. Biol. Chem./
*112,* 283). It reads as follows: “The data demonstrate conclusively that 
the crystalline compound is the new essential we have been endeavoring to 
isolate for several years. Furthermore, the experiments recorded in Chart 1 
represent the first successful efforts to induce growth in animals upon diets 
carrying synthetic mixtures of highly purified amino acids in place of 
proteins.” This work marks the discovery of threonine.
Minor J. Coon
First Published on Aug 09, 2002
Aspartate transcarbamylase activity is inhibited by CTP and activated by ATP.
Arthur B. Pardee
First Published on Jun 05, 2002
John Jacob Abel
Joseph S. Fruton
First Published on Apr 17, 2002
The bicyclic cascade that regulates GS activity. Interrelationship between 
the cyclic interconversion of the regulatory protein between uridylylated 
(PII(UMP)4) and unuridylylated (PII) forms, and the cyclic interconversion of 
GS between adenylylated (GS(AMP)12) and unadenylylated forms, and the 
reciprocal control of these interconversions by l-glutamine (Gln) and 
α-ketoglutarate (α-KG). ATa and ATd denote the adenylylation and 
deadenylylation sites of adenylyltransferase, respectively; UTd and UTudenote 
the deuridylylation and uridylylation sites of uridylyltransferase, 
respectively. Reprinted with permission from Rhee et al. (Rhee, S. G., 
Chock, P. B., and Stadtman, E. R. (1985) in The Enzymology of 
Post-translational Modification ofProteins (Freedman, P. B., and Hawkins, 
H. C., eds) Vol. 2, pp. 273–297, Academic Press, New York).
Earl R. Stadtman
First Published on Oct 03, 2001
*Functional form of lipoic acid.* The carboxyl group of lipoic acid is bound 
in amide linkage to the ε-amino group of a lysine residue in the 
acyltransferase component (/E/
2) of the α-keto acid dehydrogenase complexes. This linkage provides a 
“swinging arm” that facilitates communication between active sites.
Lester J. Reed
First Published on Jul 26, 2001
Irwin Fridovich
First Published on Jun 08, 2001
Gerty T. Cori and Carl F. Cori (c. 1947) in her laboratory.
Arthur Kornberg
First Published on Jan 05, 2001
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MINIREVIEWS

Hideharu Hashimoto, Xing Zhang, Paula M Vertino, Xiaodong Cheng
First Published on Jul 07, 2015
Suzana Markolovic, Sarah E Wilkins, Christopher J Schofield
First Published on Jul 07, 2015

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